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GLP-1 Agonism Effect in Diabetic Nephropathy As for GLP-1 (Figure 2), it has a more direct role in decreasing kidney oxidative stress, due to the presence of receptors in proximal tubular (PT) cells and kidney smooth muscle

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It induces delta-wave sleep (NREM stage 3-4), the most restorative stage of sleep, by modulating circadian rhythms and the balance between inhibitory serotonin/GABA systems and activating pathways

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